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Cosmetic ingredient approval is regulatorily distinct from drug approval
References GurtnerGCWernerSBarrandonYLongakerMTWound repair and regenerationNature200845331432118480812 RolfeKJRichardsonJVigorCIrvineLMGrobbelaarAOLingeCA role for TGF-beta1-induced cellular responses during wound healing of the non-scarring early human fetus?J Invest Dermatol20071272656266717687390 SteedDLClinical evaluation of recombinant human platelet-derived growth factor for the treatment of lower extremity ulcersPlast Reconstr Surg2006117143S149S discussion 50S51S16799381 WangLWuXShiTLuLEpidermal growth factor (EGF)-induced corneal epithelial wound healing through nuclear factor kappaB subtype-regulated CCCTC binding factor (CTCF) activationJ Biol Chem2013288243632437123843455 PlichtaJKRadekKASugar-coating wound repair: a review of FGF-10 and dermatan sulfate in wound healing and their potential application in burn woundsJ Burn Care Res20123329931022561305 HaraYMatsuuraTTsukamotoMIshizakaSSaishinMEffect of tetra-peptide isolated from interleukin 1 (IL-1) on corneal epithelial wound healing in the rabbitExp Eye Res20017210711311161726 SaikaSYin and yang in cytokine regulation of corneal wound healing: roles of TNF-alphaCornea200726S70S7417881920 KimYSLewDHTarkKCRahDKHongJPEffect of recombinant human epidermal growth factor against cutaneous scar formation in murine full-thickness wound healingJ Korean Med Sci20102558959620358003 WangXJHanGOwensPSiddiquiYLiAGRole of TGF beta-mediated inflammation in cutaneous wound healingJ Investig Dermatol Symp Proc200611112117 IlicSDrmicDFranjicSPentadecapeptide BPC 157 and its effects on a NSAID toxicity model: diclofenac-induced gastrointestinal, liver, and encephalopathy lesionsLife Sci20118853554221295044 Stancic-RokotovDSlobodnjakZAralicaJLung lesions and anti-ulcer agents beneficial effect: anti-ulcer agents pentadecapeptide BPC 157, ranitidine, omeprazole and atropine ameliorate lung lesion in ratsJ Physiol Paris20019530330811595454 KlicekRKolencDSuranJStable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disabilityJ Physiol Pharmacol20136459761224304574 SikiricPSeiwerthSRucmanRStable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tractCurr Pharm Des2011171612163221548867 SikiricPSeparovicJBuljatGThe antidepressant effect of an antiulcer pentadecapeptide BPC 157 in Porsolts test and chronic unpredictable stress in rats
95 In SHR and Lyon genetically hypertensive rats, the vasoconstrictor component was more pronounced, and/or the vasodilator component was attenuated after stimulation with Ang II
Both groups showed statistically significant improvements in fine lines and skin laxity
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There is currently no approved therapy for the heart component of the disease, and heart disease is what most patients now die from
