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Recombinant human granulocyte-macrophage colony-stimulating factor in combination with standard induction chemotherapy in de novo acute myeloid leukemia
The CAPTAIN trials noted reduced rates of depression in treated groups
Quality of evidence is graded as low to moderate by major medical organizations
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In the over 2500 participants, who were assigned to the 5, 10, and 15 mg doses of tirzepatide and placebo, the percent weight changes were both statistically and clinically significant compared with placebo
If either compound has lower-than-stated purity or content, the actual administered dose differs from the calculated dose, compromising research validity
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