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It is debilitating and can affect daily life

Gastrointestinal Overlap: A Primary Concern Both Wegovy and Orlistat are well-known for their gastrointestinal side effects, which could be a significant concern if taken together: Wegovy (semaglutide) typically causes side effects such as nausea, vomiting, diarrhea, constipation, and abdominal pain

Theres a Better Option Hers and Hims list GLP-1 options, yet pricey prepaid brand medications, no insurance acceptance, limited availability of compounded oral meds in some states, labs not included, no in-person visit option, and customer service or cancellation concerns make them a tough fit for many

Diab Care 36 , 13961405 (2013)

Heller, O.H

In such cases, lower doses are often useful to monitor tolerance