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retatrutide phase 2 trial obesity nejm 2023

retatrutide phase 2 trial obesity nejm 2023 results VisualAbstract: reduces body weight by 17.5% in patients with Retatrutide Phase 3: TRIUMPH Program – Retatrutide Phase 3: TRIUMPH Program

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Testing: Third-party analytical verification

retatrutide phase 2 trial obesity nejm 2023 results VisualAbstract: reduces body weight by 17.5% in patients with Retatrutide Phase 3: TRIUMPH Program Retatrutide Phase 3: TRIUMPH Program

Roseberry T et al

retatrutide phase 2 trial obesity nejm 2023 results VisualAbstract: reduces body weight by 17.5% in patients with Retatrutide Phase 3: TRIUMPH Program Retatrutide Phase 3: TRIUMPH Program

10.1155/2020/5150684 50 GudelskaM.DobrzynK.KiezunM.KisielewskaK.RytelewskaE.KaminskiT.et al (2023)

retatrutide phase 2 trial obesity nejm 2023 results VisualAbstract: reduces body weight by 17.5% in patients with Retatrutide Phase 3: TRIUMPH Program Retatrutide Phase 3: TRIUMPH Program

After week 24, discontinuation due to side effects dropped to just 4.2%

retatrutide phase 2 trial obesity nejm 2023 results VisualAbstract: reduces body weight by 17.5% in patients with Retatrutide Phase 3: TRIUMPH Program Retatrutide Phase 3: TRIUMPH Program

Gaschler et al., 2018)

retatrutide phase 2 trial obesity nejm 2023 results VisualAbstract: reduces body weight by 17.5% in patients with Retatrutide Phase 3: TRIUMPH Program Retatrutide Phase 3: TRIUMPH Program

While FDA approval is for premenopausal women, PT-141 works through brain pathways, not hormones

retatrutide phase 2 trial obesity nejm 2023 results VisualAbstract: reduces body weight by 17.5% in patients with Retatrutide Phase 3: TRIUMPH Program Retatrutide Phase 3: TRIUMPH Program
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