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tells the Mayo Clinic, Low levels of B-12 and other B vitamins such as vitamin B-6 and folate may be linked to depression. Studies may be inconclusive, but at the very least, a holistic and integrated approach to ones health in the form of adequate vitamins and nutrients helps achieve a more balanced biology that certainly wont hurt your overall mood

Milk thistle supplements are another way to boost glutathione levels naturally

J Hazard Mater 450:131039

Still, the comparison is instructive