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Do you feel like not making an effort or working on your normal days, and every workday feels like a heavy stone on your shoulder

A deficiency in B12 can increase susceptibility to infections and cause general fatigue

Combination data with diet suggest complementary mechanisms, and reviews highlight continued medicinal-chemistry work to tune potency, selectivity, and exposure for future translational studies

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It is characterized by symptoms such as tingling (paraesthesia), numbness, pain, temperature sensitivity, and muscle weakness in the hands and feet and can spread throughout the body

A doctor may also decide whether additional tests or repeated monitoring are needed to confirm that treatment is working