Administering a GHRP during that somatostatin-dominant window produces a blunted response which is exactly what the physiology predicts, and exactly what researchers should want to see as a validation signal
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However, although GLP-1 receptor agonists are known to produce modest but statistically significant weight loss in patients with diabetes mellitus, our knowledge of how endogenous GLP-1 regulates food intake and body weight remains limited

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