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Peak upward trends in semaglutide search probabilities were observed in the Netherlands, Norway, Poland, Saudi Arabia, and the UAE during early 2022, followed by Ireland, Serbia, South Africa, Sweden, and Switzerland in late 2022
Bissinger R, Bouguerra G, Stockinger K, Abbs S, Lang F
Among two promising antidiabetics for treating NAFLD or NASH in overweight or obese, GLP-1RA showed significantly better effects than TZD in reducing liver fat contents detected via 1 H-MRS
Skin biopsy: a new tool for diagnosing peripheral neuropathy
COA / Lab results Evidence: Clinical trial Pros Triple GLP-1 / GIP / glucagon agonism in one peptide raises energy expenditure, not appetite alone Largest weight reduction reported for an incretin-class compound (~24% at 12 mg, 48-wk phase 2) Reductions in HbA1c, visceral fat and liver-fat content across trials Once-weekly subcutaneous dosing (albumin-bound half-life) Cons GI effects require gradual multi-week dose titration Newest of the GLP-1 class phase 3 (TRIUMPH) topline only
real-world patients skip meals, drink alcohol, and pull all-nighters
