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Ultimately, the trouble with using medications like this for weight loss is that once you stop taking them, the weight tends to come back
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The glucagon arm is what distinguishes it from every GLP-1 and dual-agonist compound it increases energy expenditure in addition to the appetite and glycemic effects of the incretin receptors ( Coskun et al., Cell Metab 2022 )
PMID 10859160
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Shahid, R
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