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Research in animal models suggests that nausea associated with peripheral GLP-1 receptor agonist administration involves activation of central GLP-1 receptors in these brainstem regions that control emesis

26 Subjects were administered 0.75 mg of liraglutide as a single dose, and evaluated after a 72-hour period to determine if hepatic impairment influenced liraglutides pharmacokinetic and safety profile

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