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This study was conducted under the ethical guidelines approved by the Ko University Ethical Committee (protocol number 2023.282.IRB2.062)
Mobile phase composition, gradient parameters and column chemistry may significantly influence retention time and separation efficiency
This distinguishes it from benzodiazepines and Z-drugs commonly prescribed for insomnia
Structural Modifications & Enhanced Stability The N-terminus is modified via acetylation (addition of an acetyl group, Ac-)
[1] Other causes include autoimmune conditions, certain infections, and inflammatory states that alter B12 metabolism or binding protein production
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