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J Med Chem 50(24):61266132 Meier JJ, Nauck MA, Kranz D et al (2004) Secretion, degradation, and elimination of glucagon-like peptide-1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects
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Outlier analysis was conducted to identify incoherent data in the six independent datasets
Of the study cohort, 92% had type 2 diabetes and 86% had obesity
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These findings suggest bone-supportive effects mediated through GH/IGF-1 but do not establish clinical efficacy for osteoporosis prevention
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