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The glucagonostatic effect of GLP-1(736) that remains in the presence of exendin(939) could be abolished by the DPP-4 inhibitor sitagliptin [32] (ESM Fig

Research backs this up: when using GLP-1s to aid in weight loss, they were found to effectively reduce BMI, triglycerides, waist circumference, and total testosterone in people with PCOS, according to a 2024 meta-analysis in the Journal of Diabetes and its Complications

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Mikki may recommend combining it with hormone replacement therapy for comprehensive hormonal optimization, NAD+ therapy for cellular energy and longevity, MOTS-C for metabolic support, aesthetic treatments to complement internal wellness with external rejuvenation, and medical weight management if body composition is a primary goal