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[1] [2] Clinicians should carefully evaluate patients with persistent, severe upper GI symptoms to differentiate expected medication effects from other underlying conditions

Methods Wild type and Serpina3c knockout (Serpina3c / ) mice were fed a high-fat diet (HFD) for 12 weeks

On average, patients using these medications can achieve significant reductions in HbA1c (a marker of blood sugar control) and weight loss of around 314% of their body weight, depending on the medication and lifestyle changes

P.EguchiA.GhoshS.et al (2015)