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Since for most people it is impractical to take supplements several times a day, a single dosage of 250-500 micrograms seems to be the best solution

(7) Hong S, et al

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Serum B12 alone can sometimes be misleading MMA levels provide a more functional assessment of whether your body is actually utilizing the B12 available to it

(2021) The efficacy of intramuscular injection of vitamin B12 in the treatment of acute herpetic neuralgiaa prospective pilot study

Science 348 , 1262073 (2015)