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For nonclinical design, dose-range finding, route feasibility (i.p., s.c., osmotic minipumps), and exposureresponse mapping in the selected strain/sex/age are recommended before hypothesis testing
Funding This work was supported by grants from the National Natural Science Foundation of China (NSFC Numbers 81672800, 81603009, 81673020, 81802632, and 82173830), Natural Science Foundation of Shaanxi (2020JQ-445), and the Key Research and Development Program of Shaanxi Province (2021SF-207, 2021SF-223, and 2022ZDLSF05-19)
This area works well but can be slightly more uncomfortable than the abdomen for some researchers due to less subcutaneous fat
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In order for B12 to be absorbed from the gut, it requires a specific protein called intrinsic factor (IF)
Bias in meta-analysis detected by a simple, graphical test
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