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In contrast, T2 low asthma may involve neutrophilic or pauci-granulocytic inflammation with cytokines, such as IL-6, IL-8, IL-17 and tumor necrosis factor alpha (TNF-), playing key roles in neutrophil recruitment and chronic inflammation

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According to NICE Clinical Knowledge Summary guidance, patients with neurological involvement should receive more intensive initial treatment to optimise recovery potential

Johnson DA, Fennerty MB

Its important for adults thinking about or getting B12 injections to know about these