Glutathione and GSTs, which can make up to 10% of cellular proteins depending on the cell type, are essential for the neutralization of reactive electrophilic drug metabolites produced by phase I enzymes
10.1007/5584_2021_690 25 MenjivarN
Less attention is paid to whether its safe
Overall, irreparable damage to membranous organelles, spindle microtubules, cellular DNA, and the heat shock system itself leads to profound dysfunction of gametes and embryos and even apoptotic cell death, all of which adversely impact fertility (84, 85, 107, 109, 110, 152, 153)
Oral glutathione is less effective due to poor absorption
10.1016/j.bbamem.2016.02.020 82.0 82.1 Pham TL, Bazan HEP: Docosanoid signaling modulates corneal nerve regeneration: effect on tear secretion, wound healing, and neuropathic pain