Significant improvements in beta-cell activity are indicated by HOMA2-B percent change from baseline increases ranging from 93 to 163% for tirzepatide (5, 10, and 15 mg doses), outperforming dulaglutide and placebo effects
New Cleveland Clinic Study Reveals Real World Insights Diabetes Care: Efficacy and Safety of GLP-1 Medicines for Type 2 Diabetes and Obesity Mayo Clinic: Type 2 Diabetes: When Is It Time to Ask Your Care Team About GLP-1s and Weight Loss
If that hypothesis holds, two things follow
The several opinions by the Justices are lengthy (a total of 193 pages in the "slip opinion" released by the Court and 81 pages in the version published
If the temperature remained below -10C, the peptides are likely stable
For GLP-1 medications specifically, this faster absorption can translate to a slightly quicker onset of appetite suppression after each dose, which is directly relevant when your goal is fat loss