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These genetic abnormalities were identified in about 10% of infants following sulfonylurea exposure, 8% with GLP1R agonists, 7% with SGLT2 inhibitors, and 6% with DPP-4 inhibitors compared to about 8% with insulin

The reduced hunger and early satiety mean patients often struggle to meet the UK Reference Nutrient Intake (RNI) for protein of 0.75g per kilogram of body weight per day, or higher amounts (1.0-1.2g/kg for older adults

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doi: 10.1054/DRUP.2000.0175 210 ZhouX.LiaoF.YeZ.ChengJ.ZhuJ.ChenX.et al

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Differential effects of GLP-1RAs on the risk of diverse tumor types Currently, several GLP-1RAs have been approved for the treatment of type 2 diabetes (T2DM) and/or obesity, and emerging evidence suggests that these agents may influence cancer risk