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In receptor-driven systems, researchers can often connect ligand binding, receptor activation, downstream signaling, and biological outcome in a relatively linear sequence

Sikiric et al., 2020b) and complications (for review, see Sikiric et al., 2020b)

Peptide-based approaches can mitigate off-target effects with molecular specificity and facilitate tailored treatment regimens informed by genetic, hormonal, or biomarker signatures

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