Semaglutide was initiated at a dose of 0.25 mg once weekly, and the dose was increased every 4 weeks in accordance with recommended dosing (from 0.25 mg to 0.5 mg, 1.0 mg, 1.7 mg, and 2.4 mg) until the 2.4-mg dose was reached

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Patients and their doctors will want to make decisions about medications and specific doses together, she said
Am J Physiol Renal Physiol (2013) 304:F13744
Of note, it is well-established that a rapid decrease in HbA1c can worsen diabetic retinopathy, particularly in patients with long-term and uncontrolled diabetes [71]
I feel much better