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patients and clinicians should refer to the most current published trial results and, once available, the approved SmPC
This vascular mechanism may help explain why GLP-1RAs consistently show reduced dementia incidence in large observational cohorts, even when effects on amyloid burden or short-term cognition are modest [13,14,15]
Vincent JA, Mohr S
doi: 10.1186/1477-7525-9-83 Summary Keywords diabetes mellitus, glucagon-like peptides, hypoglycemic agents, adults, Colombia Citation Buenaventura-Collazos DC, Garca-Ramos AF, Balczar-Valencia CM, Aguilar-Londoo C, Coronel-Restrepo N, Monsalve-Arango CY, Cuesta-Castro DP and Ramrez-Rincn A (2024) Effectiveness and safety of once-weekly semaglutide: findings from the SEMACOL-REAL retrospective multicentric observational study in Colombia
Phase 2 trial data showed no plateau at the 48-week endpoint
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