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Some patients may need longer at each dose level
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This regulatory framework exists because GLP-1 drugs work on multiple biological systems and individual responses vary based on genetics, kidney function, and medication interactions
34, 35, 36, 37, 38, 39 However, it is unknown if GLP-1R occurs on PSCs in normal pancreas, on activated PSCs in AP or CP or if this does occur, whether the GLP-1R agonists affect the PSC signaling cascade, PSC growth or ability to release inflammatory mediators
They act as signalling molecules within the body, instructing other cells and molecules on what functions to perform
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