The effects of GLP-1 RAs on obesity are not solely due to weight loss, but some pleiotropic effects like decreased inflammation, oxidative stress, and fibrosis also play a role in some of the complications
Hepatol Int
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oral peptide delivery requires special formulations (e.g., SNAC technology for oral semaglutide) For more on delivery methods, see our guide on peptide bioavailability and routes of administration
However, it should not be interpreted as proof of clinical gastrointestinal benefit
T statistics were used to assess the significance of the time effect (on the log scale) by pairwise comparison to the control group for each organ