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Salloum, A., Bazzi, N., Maalouf, D., & Habre, M
Intestinal permeability occurs when holes develop in the intestinal barrier, often due to damage caused by: Adrenal fatigue Alcohol Capsaicin (in spicy peppers) Dental infections Dysbiosis Enzyme deficiencies Food sensitivities Gluten Gut infections Nonsteroidal anti-inflammatory drugs (NSAIDs) Nutrient depletions Psychological stress Small intestinal bacterial overgrowth (SIBO) Sinus infections Strenuous exercise Stress Surgery or trauma Toxins These holes in the intestinal lining allow for toxins and food particles to leak into the bloodstream, and the body labels these molecules as foreign invaders
Subcutaneous injection places the peptide in the fatty tissue layer between skin and muscle, where it absorbs gradually and migrates to damaged areas
Exposure is primarily through contaminated foods such as cereals, grape juices, dairy, spices, wine, dried vine fruit, and coffee
The peptide works through multiple pathways including angiogenesis (formation of new blood vessels), collagen synthesis enhancement, and growth factor modulation
Further, mTH one deficiency shows mitochondrial DNA oxidative damage when reduced expression of cytochrome C oxidase 1, indicating that targeting mTH one could be a potential strategy to prevent thrombotic events (Figure 3 depicts the molecular mechanism of platelet hyperactivation in DM
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