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ACS Chem Neurosci 10:41904198 Vezzani A, Aronica E, Mazarati A, Pittman QJ (2013) Epilepsy and brain inflammation
While body weight and metabolic phenotypes remain the primary endpoints, the outcome spectrum is progressively extending toward lipotoxic load [e.g., hepatic fat and visceral adipose tissue (VAT)], inflammatory/cardiometabolic risk markers, and reproductive outcomes with higher clinical decision-making value, such as menstruation, ovulation, and pregnancy
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JAMA Network Open, 6 (3), e236185
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To minimise side effects and allow the body to acclimatise to the medication, it is recommended to start semaglutide at a low dose of 0.25mg or 0.5mg per week for 1 month, before increasing to a medium dose of 1mg per week
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