Phosphorylation of IRS-1 or IRS-2 activates phosphoinositol 3-kinase (PI3K)-PDK1-AKT signaling pathway, while phosphorylation of Shc leads to activation of RAS, RAF and extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) signaling pathway
Carvalho AF, Macdo DS, Goulia P, Hyphantis TN
Data availability The authors declare that data supporting the findings of this study are available within the article and its Supplementary Information files and from the corresponding author upon reasonable request
Maintenance / Long-Term Research Protocol Amount: 200300mcg Frequency: 35 days weekly Duration: Variable depending on research design Research Notes Lower-frequency protocols are sometimes investigated in maintenance-focused research protocols
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