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Furthermore, viral DNA that enters the chromosome of the infected cell (where it combines with the cell's own DNA by the action of the HIV-integrase enzyme) may remain in a latent state
this effect occurs through the modulation of protein tyrosine phosphatase activity in IGF-1 signaling
In neuroblastoma cells, Epitalon reduced levels of 8-hydroxydeoxyguanosine (8-OHdG), a key marker of oxidative DNA damage that accumulates in aging neurons and is elevated in Alzheimers and Parkinsons disease [51]
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