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doi: 10.1016/j.acuro.2019.10.007

3.4 HSF activation and nuclear translocation phase Upon heat stress, HSF1 monomers are released from the inhibitory chaperone complexes and rapidly form trimers (Figure 2b)

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Two 2.5 mg injections spaced 3.5 days apart produce a curve where the peak is only about 1.2 times the trough

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Importantly, short telomeres correlate with chromosomal instability, impaired maturation, and reduced reproductive success [69, 70]