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Ascorbate deficiency lowers the activity of microsomal drug-metabolizing enzymes and cytochrome P-450 electron transport

While the concern is worth observing, it does not seem to be scientifically proven

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Medication Interactions to Consider When taking glutathione, you should be particularly careful if you're also on other medications

Despite these positive data, one needs to be cautious since USP7 inhibitors suffer the same caveat as Nutlins: they only stabilize and accumulate wild-type p53, whereas the majority of tumors harbor p53 mutants

10.1212/WNL.0000000000003391 506 ZhangJ.LiuK.SunL.YangL.LiuX.ZhuY.et al