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stop at least 2 months before conception Ibuprofen caution / NSAIDs increase GI bleeding risk and may blunt renal function alongside GLP-1 drugs Wegovy FDA label / approved for BMI 30, or 27 with at least one weight-related comorbidity SELECT trial / semaglutide 2.4 mg cut major cardiovascular events by 20% over 3.3 years in adults with obesity Does Caffeine Interfere With GLP-1 Medications

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It is important to note that there is no official link established between Wegovy and worsening of autoimmune thyroid disease

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Data availability All RNA-seq data have been deposited in the GEO and are accessible through GEO Series accession numbers GSE272456 (HCT116) and 810 GSE272391 (AKP organoids) or at RNA-seq data of the clinical cohort have previously been deposited at GSE103479 (ref