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Hsieh J, Aimone JB, Kaspar BK, Kuwabara T, Nakashima K, Gage FH

These are among the largest weight-loss figures reported for any pharmacological agent in a Phase 2 obesity trial

Norethisterone is not a contraceptive when used to delay your period, so you must still use other forms of contraception, like a condom

The skin changes are not dramatic at 8 weeks but become clinically visible at the 12 to 16-week mark in most patients

Constipation Paradoxically, some individuals experience constipation rather than diarrhea, likely related to delayed gastric emptying effects

Some absorption occurs, especially when copper stabilizes the peptide, but the amount reaching the bloodstream intact is still under study