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-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

To investigate the role of the integrin-FAK pathway in 25HC-mediated activation of a proinflammatory response in a pathophysiological setting, mimicking IAV infection, we administered 25HC to the mouse airway either in the presence or absence of a 1 integrin blocking antibody, previously employed to inhibit integrin activation in the mouse airway 45 , or the FAK inhibitor (PND-1186), which has been used in mice to block FAK activation 46

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BPC-157 is a synthetic peptide composed of 15 amino acids and is commonly categorized among research peptides used in laboratory environments