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If the main functional output of 2A R-D 4 R heteromers is a decrease in excitability of P neurons (see below, section 6) this could provide an additional mechanism for the gain of function of D 4.7 R in its inhibitory control of frontal cortico-striatal neurotransmission ( Figure 2 )
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Skin, tendons, ligaments, and connective tissues all require constant collagen turnover
due to a strictly vegetarian diet)
Recovery is a multi-layered process
