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The degree to which leptin and insulin stimulate overall GLP-1 secretion is still unclear, but GIP-mediated GLP-1 release has been shown to occur in rodents via acetylcholine release by the enteric nervous system
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Notifications for Structure/Function and Related Claims in Dietary Supplement Labeling
& Heaton, K
The prescribing information explicitly states it must be made approximately isotonic prior to use
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