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Linus Pauling Institute Oregon State University Updated in August 2021 by: Victoria J

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For those living with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), mast cell activation syndrome (MCAS), and dysautonomia, this profound exhaustion and cognitive dysfunction is an all-too-familiar reality

The published volume limits are: Abdomen: 1.5 mL maximum per site Thigh: 1.0 mL maximum per site Upper arm: 0.5 mL maximum per site These limits come from a 2014 pharmacokinetic study (Usach et al., Journal of Controlled Release ) that measured solution retention after subcutaneous injection at increasing volumes

Inform patients about the signs of serious skin reactions