The mutation in ALDH4A1 leads to the accumulation of pyrroline-5-carboxylate (P5C) in the mitochondria, which can react with PLP to cause PLP deficiency in the brain and can also be converted to proline, resulting in elevated plasma proline levels (Fig
In general, serious side effects from B12 injections are rare but in some cases, people may experience a few mild ones including pain, redness, or bruising at the site of injection
However, an oral B12 dose is often larger because your body usually doesnt absorb it all
It was slow progress with some symptoms getting worse before better
If you want to see how the programs themselves work and what patients experience on them, that lives on our Rapid and Standard Weight Loss Programs page
There is no set timescale as we are all different