Hypoxia stress was modeled by placing rats into a flow pressure chamber for 15 minutes under 0.26 bar, which simulates an altitude of 10,000 m above ground level
Oral formats of SLU-PP-332 therefore have no published evidence of producing the systemic ERR agonism observed in the IP-route mouse studies
Seiwerth, S., Sikiric, P., Grabarevic, Z., Zoricic, I., Hanzevacki, M., Ljubanovic, D., Coric, V., Konjevoda, P., Petek, M., Rucman, R., Turkovic, B., Perovic, D., Mikus, D., Jandrijevic, S., Medvidovic, M., Tadic, T., Romac, B., Kos, J., Peric, J.,
Diagnosis : Elevated thyroid hormones, suppressed TSH, history of recent iodine exposure (contrast agents, supplements)
Third, and decisively, no one has measured the actual repair or angiogenic output of KLOW in a human being
The culture medium was changed every day to avoid NAC inactivation