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J Membr Biol 69:112 Mulcahy RT, Bailey HH, Gipp JJ (1995) Transfection of complementary DNAs for the heavy and light subunits of human gamma-glutamylcysteine synthetase results in an elevation of intracellular glutathione and resistance to melphalan
Curr Med Chem 21:36363645
Is it effective
Even at high doses, researchers have found NAC to be safe and well-tolerated
In animal studies, its also been shown to help modify the response to stress by suppressing the increase of phosphorylated stress-activated protein kinase, which raises inflammation
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