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When he studied the lizards venom, he discovered that its saliva contained a hormone called exendin-4, which worked much the same way as GLP-1, but lasted much longer
[3] Neutral endopeptidase 24.11 (NEP 24.11) is a membrane-bound zinc metallopeptidase widely expressed in several tissues, but found in particularly high concentrations in the kidneys, which is also identified accountable for the rapid degradation of GLP-1