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For most people, dietary sources provide everything that is needed
This can increase your need for B12 supplementation, and injections may be especially helpful in these cases
Just remember that although supplements are generally effective, youll typically only absorb about 50-60% of the vitamin B12 itself because of bioavailability
Fatal hypokalemia may occur when severe megaloblastic anemia is treated intensively with vitamin B12, as a result of increased erythrocyte potassium requirements
2014;349:g5226
The presence of comorbidities can significantly impact the pharmacokinetics of Vitamin B12, making it essential to adjust dosing protocols. Expert Opinion on Vitamin B12 Therapy Genetic Factors Affecting B12 Metabolism Genetics play a role in how well someone can use Vitamin B12
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