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Key points GLP-1 receptor agonists may reduce alcohol cravings and intake
These small molecules bind to mRNA and prevent it from being translated into a protein in the cell ribosome, thus abrogating the downstream effects of that proteins signaling (Chan 2006
eLife, 14, e12270663
In contrast, only 27% of those on placebo saw a weight reduction of at least 5%
That depth of evidence gives us substantially more confidence in its mechanisms and effects than we can have with newer, less-studied compounds
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