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Short-acting GLP-1RAs might cause more GLP-1 induced gastroparesis because they slow stomach emptying more dramatically
Patients often report a transformation that includes: Fuller, youthful cheeks in the "before" photo Noticeable hollowing under the eyes and along the temples in the "after" A more angular or aged appearance, even if the body overall looks slimmer Before and after examples include: Sunken cheeks and thinner jawline Wrinkles becoming more visible due to lost support under the skin Sagging skin in people over 40 These symptoms are more pronounced in patients with naturally leaner faces or older adults with lower collagen levels
the medial prefrontal cortex mPFC(Carvalho Pereira et al., 2018)
Research has shown that estrogen deficiency (as in menopause) leads to decreased GLP-1 secretion, and estrogen replacement reverses this effect [3]
Big questions remain, she adds
Data curation: Kunkun Liu
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