As the newest addition to incretin-based drugs, tirzepatide harbors the potential to counteract most of the pathogenetic mechanisms underpinning CKD in T2D displaying unprecedented features in terms of glucose and weight lowering, accompanied by promotion of insulin sensitivity, control of SBP, dyslipidemia, and biomarkers of inflammation and endothelial dysfunction
Semaglutide also sold as the oral formula Rybelsus works mainly by helping control blood sugar
Users of these drugs consume 15-40% fewer calories compared to placebo groups and exhibit reduced cravings for sweet, salty, fatty and alcoholic foods, leading to notable changes in dietary patterns
They also have demonstrated anti-inflammatory effects
How long does the procedure take
Further investigations are needed to comprehensively assess the functional and safety aspects of long-term Exe4 secretion