It downregulated ACSL4 and CD71 expression, significantly increased the expression of System Xc , GPX4, and Ferritin, reduced ROS levels, and inhibited ferroptosis, inflammatory responses, and mitochondrial dysfunction in BV2 cells
[5, 6] It is considered the main redox buffer in human cells owing to its large amount of reducing equivalents, [7] and is an important enzyme cofactor that serves as a neuromodulator in the central nervous system
Flavonoids were quantified using peak areas of A 280nm , A 500nm or selective ion monitoring in positive mode with external calibration curves prepared in the same solvent as the samples
Chauveau C, Rmy S, Royer PJ, Hill M, Tanguy-Royer SV, Hubert FO-X, et al
Role of carnitine in cancer chemotherapy-induced multiple organ toxicity
Other studies have explored the role of estrogen in protecting from ROS [116] and cellular senescence [117]