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Setting a VLCKD protocol that includes meal replacements provides enhanced safety, effectiveness, and adherence in patients with obesity
Although the tissues involved in tocochromanol catabolism are not well identified, CYP4F2 is expressed in liver and kidney (18), as well as intestine (19)
Per-component breakdown (fixed ratio)
Additional requirements can be imposed on a case-by-case basis, including collection of safety data using an Australian patient registry, enhanced communications to health care professionals and patients, more frequent or more prolonged submission of Periodic Benefit-Risk Evaluation Reports (PBRER) and possible selection of product for TGA laboratory testing
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