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How Genetic Predispositions Inform Metabolic Risk Context Genetic variations in GLP-1 receptor pathways, appetite-regulation genes (like MC4R and FTO), and glucose metabolism influence how individuals metabolize food and respond to therapy
The regulatory mechanisms of TMAO-induced autophagy in different cells are shown in Figure 4
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GLP-1 agonists reduce appetite , which contributes to their role in weight management
GLP-1 medications can already affect gastrointestinal motility, so adding bitter orange extract could lead to side effects like nausea or increase cardiovascular risks
As illustrated in Fig
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