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Ferroptosis in TECs is repaired in GPX4-overexpressing mice during UUO The findings of pharmacological experiments effectively illustrated that inhibiting TEC ferroptosis can rescue renal fibrosis through TGF-/Smad signaling
Ascorbic acid has also been studied in the therapeutic setting for cancer patients, considering that high doses act as pro-oxidants rather than antioxidants and can limit the glycolysis-dependent energy production of cancer cells by hindering transporter-mediated glucose intake (117, 123)
nice.org.uk/guidance/ng247 Cozzolino M, Busnelli A, Pellegrini L, Riviello E, Vitagliano A
C.TramperJ.et al
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150 Interestingly, aspirin exhibits a dual role in cancer cell proliferation
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