If weight loss has slowed or appetite control has changed while remaining on the same dose, moving to a higher dose may be discussed as part of your treatment plan
Presented for research literature review only Smits MM et al
Listen to your body and adjust your timing (using the 72-hour rule) if needed
Tirzepatide may also cause additional stomach issues such as constipation, belching, indigestion, and fatigue, and there is a possible risk of low blood sugar, especially when combined with other diabetes medications
Hyperinsulinemic-euglycemic clamp studies demonstrated post-prandial hyperinsulinemia and a significant decrease in peripheral post-prandial insulin sensitivity in both hyperprolactinemia obese and non-obese subjects (27, 69)
Eating smaller, more frequent meals rather than large portions can help accommodate delayed gastric emptying and reduce feelings of excessive fullness and nausea